Well, I'm a guy so I guess it's a bit different.
But I've had some truly aweful migranes, the first one I had sent me strapped in a wheelchair to hospital for a few days. No drugs worked, as I'd just throw them up or the pain would just last through whatever I took.
And, embaressing as it is, I jerked off like a 15 year old, it's truly the only way to escape the pain... at least for about 5 seconds while the orgasm lasts, and then the pain is back, but that reprive allows you to hold out a little longer.
I've heard that LSD (Acid, hallucinogenic drug) is supposed to be amazing at stopping migranes, which is quite interesting. Although you would be tripping instead.