More than likely she has seen the passing of her grandparents and the knowledge of their problems prior to, figgers she will get it anyway so who cares.
If she doesn't do things you enjoy? If they are things you enjoy and you are not happy, then move on.
As much as we love people, we can not change them.
I wish there was something else I could think of that may help but she needs to see someone to believe in herself again, to realise that you are part of her life as well and therefore it is not all about her, that you love her it is not all about her.
It's not about weight rather love.
Perhaps show her this thread.
CW
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