I have done a lot of research into relationship theory and and associated scientific study. The sites that backed up what they were saying with scientific research all point to the role of a hormone called Oxytocin in long term relationships.( It is being heavily researched because drug companies see the potential financial benefits.)
This hormone regulates all human relationships whether they be same sex friendships/life pairs or Parent child. If you Google Cupids Poison Arrow you will be able to check it out for yourself. Oxytocin levels can be manipulated to your benefit in a relationship with the right behaviours.
Even divorce stats will show that successive relationships have less chance of success and I think that this is the case because people don't change behaviour they just change lovers.
Good luck.
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